Week 18 (2017)

Potential new target for cancer treatment

Summary: Inhibition of the enzyme RIOK1could stop the growth of tumors and the development of metastases
Interest Group: Research
Research Organization: University of Freiburg
Journal Article: EBioMedicine The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior.
Full Press Release: Distributed by ScienceDaily
ID: HN1585-004


New microscopic technique could help detect, diagnose metastatic melanomas

Summary: The fight against skin cancer just got a new weapon. Researchers have devised a new tool to detect and analyze single melanoma cells that are more representative of the skin cancers developed by most patients. The study outlines the new techniques that could lead to better and faster diagnoses for the life-threatening disease.
Interest Group: Research
Research Organization: University of Missouri-Columbia
Journal Article: The Analyst Spectrophotometric analysis at the single-cell level: elucidating dispersity within melanic immortalized cell populations.
Full Press Release: Full Press Release: Distributed by ScienceDaily
ID: HN1585-008


MRSA blood infections are less fatal in kids, but cause significant complications

Summary: Children with bloodstream infections caused by methicillin-resistant Staphylococcus aureus (MRSA), a common antibiotic-resistant bacteria, are less likely to die than adults with this condition and have different risk factors for treatment failure, a new study indicates.
Interest Group: Kids
Research Organization: Children’s National Health System
Journal Article: Pediatrics Community Poverty and Child Abuse Fatalities in the United States.
Full Press Release: Distributed by ScienceDaily
ID: HN1585-012


Pac-Man-like CRISPR enzymes have potential for disease diagnostics

Summary: Researchers have found 10 new variants of the Cas13a enzyme, the Pac-Man of the CRISPR world, that hold promise for disease diagnostics. Seven of these are like the known Cas13a enzyme, which binds RNA and, once activated, indiscriminately chews up all RNA. Three, however, bind and cut at different RNA nucleotides, and could be used in combination with the known Cas13a enzyme to simultaneously detect two types of viral RNA for multiplexed diagnostics.
Interest Group: Research
Research Organization: University of California – Berkeley
Journal Article: Molecular Cell RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes.
Full Press Release: Distributed by ScienceDaily
ID: HN1585-020